Collaborative Longitudinal Evaluation of Keratoconus


The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study Archive


The CLEK Study was a multi-center, observational study whose purpose was to prospectively characterize vision, corneal changes, and patient quality of life in Keratoconus and to determine the progression of changes occurring with Keratoconus over time.

Over 1,200 keratoconus patients were enrolled at 15 participating clinics across the United States, examined at enrollment (between May 1995 and June 1996) and annually through 8 years of follow-up (the last 8-year follow-up was completed in August 2004).

This web site, part of the official CLEK Study archive compiled after study close, contains extensive documentation of the study's protocol and procedures, detailed documentation of study forms, an introduction to the database, copies of internal newsletters and a bibliography of publications.

 

History and Overview

 

Protocol and Procedures

 

Study Oversight

 

Publications

 

Reading Centers

 

Forms and Database Documentation

 

Contact Information


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Last Modified: May 9, 2006
Copyright 2005